$11 Million in Funding Available in Cancer Research and Technology for Innovative Small Businesses

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2016 NCI SBIR Contract Topics
Applications due by 5:00 p.m. ET on October 16, 2015

Does your small business need early stage financing to take its cancer research to the next level? The National Cancer Institute Small Business Innovation Research (NCI SBIR) has released 14 new contract funding opportunities for qualified small businesses to help advance the research, development, and commercialization of cancer research and technology in priority areas.

If your small business needs early stage financing to advance its cancer research and technology development, the NCI SBIR can help. The NCI solicits proposals for SBIR contracts only one time per year, so don’t miss your chance! Applications are due by 5:00 p.m. ET on October 16, 2015. For more information about this solicitation please see Guide Notice NOT-OD-15-130.

Note that NCI now accepts applications electronically. Paper proposals will not be accepted.

Review the opportunities below and apply today!

For more details on NCI contract funding opportunities, please visit the Contract Topics page on our website. An informational webinar will be held on August 13, 2015 at 2:00 p.m. ET. Register for the webinar here. Following registration, a confirmation e-mail will be sent containing information about joining the webinar.

NCI SBIR Contract Topics Funding Opportunities 

The PHS 2016-1 solicitation includes the following contract topics:

Topic No.              Topic Title

NIH/NCI 341: Development of Metabolomics Data Integration Methods and Software

NIH/NCI 342: Validation of Mobile Technologies for Clinical Assessment, Monitoring and Intervention

NIH/NCI 343: An Electronic Platform for Cognitive Assessment in Cancer Patients

NIH/NCI 344: Technologies for Differential Isolation of Exosomes and Oncosomes

NIH/NCI 345: Predictive Biomarkers of Adverse Reactions to Radiation Treatment

NIH/NCI 346: Molecularly Targeted Radiation Therapy For Cancer Treatment

NIH/NCI 347: Signal Amplification to Enable Attomolar Quantitation in Slide-Based or ELISA Biomarker Immunoassays

NIH/NCI 348: Identification and Capture of Enriched Tumor Zones with Preservation of Labile Biomarkers from Ultra-Cold Biopsies

NIH/NCI 349: Proximity Slide Based Sandwich Immunoassay to Visualize Intramolecular Epitopes of Analytes in Tissue Sections

NIH/NCI 350: Highly Innovative Tools for Quantifying Redox Effector Dynamics in Cancer

NIH/NCI 351: Modulating the Microbiome to Improve Efficacy of Cancer Therapeutics

NIH/NCI 352: Cell and Animal-Based Models to Advance Cancer Health Disparity Research

NIH/NCI 353: Cell-Free Nucleic Acid-Based Assay Development for Cancer Diagnosis

NIH/NCI 354: Companion Diagnostics for Cancer Immunotherapies

Get answers to some frequently asked questions.

Learn more about the difference between SBIR contracts and grants.

If you have questions about any of the topics or general questions on contract administration, please contact:

Ms. Rosemary M. Hamill
E-mail: ncioasbir@mail.nih.gov

Please include Solicitation PHS 2016-1 and the Topic Number when submitting questions. 
Be sure to continue to check our website for updates and events. For a full list of funding opportunities currently available from the NCI SBIR & STTR Programs, please visit the Funding page

The SBIR & STTR Programs are NCI’s engine of innovation for developing and commercializing novel technologies and products to prevent, diagnose, and treat cancer. The SBIR & STTR Programs are government set-aside programs for domestic small businesses to engage in research and development that has the potential for commercialization and public benefit.

Sign up to receive updates about
SBIR & STTR funding opportunities at


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